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3 celline classic 1000 bioreactor culture devices
Disposable two compartment flask for suspension cells, 1000 ml media volume, cells are trapped in a 15 ml culture volume
Disposable Bioreactor for Efficient Protein Expression
* Monoclonal antibody production in hybridomas
* Recombinant protein expression in transfected cells
* Continuous culture maintenance for long-term studies
Easy and economical protein expression
Due to its uncomplicated design working with the CELLine bioreactor is as simple as with any standard tissue culture flask. For a straightforward control of the growth process, microscopic observation of the cells is made possible by the transparent design of the CELLine classic bioreactor. The system operates independently of any complicated control technology and works without any pump systems or agitation devices. Easily and securely stackable, CELLine flasks occupy a minimum of space in any standard CO2 incubator.
A specific adaptation of the cell culture techniques or media composition is generally not necessary when starting to work with CELLine and both, serum-supplemented or serum free media are suitable.
CELLine has been designed to bring substantial cost savings to cell cultivation. Labour costs are considerably reduced, because fewer disposable flasks need to be handled compared to other culture techniques in order to produce milligram amounts of protein. Also the expenses for media supplements are significantly reduced, since the addition of serum or other synthetic additives can be limited to the cell compartment. Furthermore, the high production yield and quality obtained in the relatively small culture volume of CELLine contribute to reduce costs and labour time in the subsequent downstream processing steps of the product.
CELLine is a disposable bioreactor that is competitive in costs and performance to the production of monoclonal antibodies using mice ascites. As an added benefit, when expressing monoclonal antibodies in hybridomas using CELLine, the antibody preparation is free of any contamination from mouse immunoglobulins. Over recent years, CELLine technology has been successfully adopted worldwide for the production of monoclonal antibodies and thereby has contributed diminishing the use of laboratory mice.
MADE IN THE USA BY WILSON WOLF MANUFACTURING
